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Secretion of Human Serum Albumin by Kluyveromyces lactis Overexpressing KlPDI1 and KlERO1

The control of protein conformation during translocation through the endoplasmic reticulum is often a bottleneck for heterologous protein production. The core pathway of the oxidative folding machinery includes two conserved proteins: Pdi1p and Ero1p. We increased the dosage of the genes encoding th...

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Detalles Bibliográficos
Main Authors: Lodi, Tiziana, Neglia, Barbara, Donnini, Claudia
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2005
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1183311/
https://ncbi.nlm.nih.gov/pubmed/16085825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.71.8.4359-4363.2005
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