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Perturbed Amelogenin Secondary Structure Leads to Uncontrolled Aggregation in Amelogenesis Imperfecta Mutant Proteins

Mutations in amelogenin sequence result in defective enamel, and the diverse group of genetically altered conditions is collectively known as amelogenesis imperfecta (AI). Despite numerous studies, the detailed molecular mechanism of defective enamel formation is still unknown. In this study, we hav...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Lakshminarayanan, Rajamani, Bromley, Keith M., Lei, Ya-Ping, Snead, Malcolm L., Moradian-Oldak, Janet
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3003358/
https://ncbi.nlm.nih.gov/pubmed/20929860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.131136
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