Perturbed Amelogenin Secondary Structure Leads to Uncontrolled Aggregation in Amelogenesis Imperfecta Mutant Proteins

Mutations in amelogenin sequence result in defective enamel, and the diverse group of genetically altered conditions is collectively known as amelogenesis imperfecta (AI). Despite numerous studies, the detailed molecular mechanism of defective enamel formation is still unknown. In this study, we hav...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Lakshminarayanan, Rajamani, Bromley, Keith M., Lei, Ya-Ping, Snead, Malcolm L., Moradian-Oldak, Janet
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2010
Gaiak:
Molecular Biophysics
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3003358/
https://ncbi.nlm.nih.gov/pubmed/20929860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.131136
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