Dynamic Control of Glutamatergic Synaptic Input in the Spinal Cord by Muscarinic Receptor Subtypes Defined Using Knockout Mice

Activation of muscarinic acetylcholine receptors (mAChRs) in the spinal cord inhibits pain transmission. At least three mAChR subtypes (M(2), M(3), and M(4)) are present in the spinal dorsal horn. However, it is not clear how each mAChR subtype contributes to the regulation of glutamatergic input to...

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Bibliographic Details
Main Authors: Chen, Shao-Rui, Chen, Hong, Yuan, Wei-Xiu, Wess, Jürgen, Pan, Hui-Lin
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2010
Subjects:
Neurobiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3003341/
https://ncbi.nlm.nih.gov/pubmed/20940295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.176966
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