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Signaling Mechanisms Mediating Muscarinic Enhancement of GABAergic Synaptic Transmission in the Spinal Cord

Activation of muscarinic acetylcholine receptors (mAChRs) inhibits spinal nociceptive transmission by potentiation of GABAergic tone through M(2), M(3), and M(4) subtypes. To study the signaling mechanisms involved in this unique mAChR action, GABAergic spontaneous inhibitory postsynaptic currents (...

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Detalhes bibliográficos
Main Authors: Zhang, Hong-Mei, Chen, Shao-Rui, Cai, You-Qing, Richardson, Timothy E., Driver, Larry C., Lopez-Berestein, Gabriel, Pan, Hui-Lin
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2646800/
https://ncbi.nlm.nih.gov/pubmed/19110040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2008.11.039
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