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The Hsp70 chaperone machinery: J-proteins as drivers of functional specificity

Hsp70s, ubiquitous molecular chaperones, function in a myriad of biological processes, modulating polypeptides’ folding, degradation and translocation across membranes, as well as protein-protein interactions. This multitude of roles is not easily reconciled with the near conformity of biochemical a...

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Detalhes bibliográficos
Main Authors: Kampinga, Harm H., Craig, Elizabeth A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3003299/
https://ncbi.nlm.nih.gov/pubmed/20651708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrm2941
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