Induction of ΔNp63 by the Newly Identified Keratinocyte-Specific Transforming Growth Factor β Signaling Pathway with Smad2 and IκB Kinase α in Squamous Cell Carcinoma

The expression of p63 (TP63/p51) occurs in the basal cells of stratified epithelia and is strongly enhanced at the early stages of squamous cell carcinomas (SCCs) of the head and neck, skin, cervix, and others. We analyzed a promoter/enhancer region (2kΔN) that drives the predominant expression of Δ...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Fukunishi, Nahoko, Katoh, Iyoko, Tomimori, Yoshiya, Tsukinoki, Keiichi, Hata, Ryu-Ichiro, Nakao, Atsuhito, Ikawa, Yoji, Kurata, Shun-ichi
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Neoplasia Press Inc. 2010
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3003132/
https://ncbi.nlm.nih.gov/pubmed/21170261
Tagiau: Ychwanegu Tag
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