Trehalose-recycling ABC transporter LpqY-SugA-SugB-SugC is essential for virulence of Mycobacterium tuberculosis

Mycobacterium tuberculosis (Mtb) is an exclusively human pathogen that proliferates within phagosomes of host phagocytes. Host lipids are believed to provide the major carbon and energy sources for Mtb, with only limited availability of carbohydrates. There is an apparent paradox because five putati...

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Bibliografiske detaljer
Main Authors: Kalscheuer, Rainer, Weinrick, Brian, Veeraraghavan, Usha, Besra, Gurdyal S., Jacobs, William R.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2010
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3003129/
https://ncbi.nlm.nih.gov/pubmed/21118978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1014642108
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