Genetic landscape of high hyperdiploid childhood acute lymphoblastic leukemia

High hyperdiploid acute lymphoblastic leukemia (ALL) is one of the most common malignancies in children. It is characterized by gain of chromosomes, typically +X, +4, +6, +10, +14, +17, +18, and +21,+21; little is known about additional genetic aberrations. Approximately 20% of the patients relapse;...

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Bibliographic Details
Main Authors: Paulsson, Kajsa, Forestier, Erik, Lilljebjörn, Henrik, Heldrup, Jesper, Behrendtz, Mikael, Young, Bryan D., Johansson, Bertil
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2010
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3003126/
https://ncbi.nlm.nih.gov/pubmed/21098271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1006981107
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