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Genetic landscape of high hyperdiploid childhood acute lymphoblastic leukemia

High hyperdiploid acute lymphoblastic leukemia (ALL) is one of the most common malignancies in children. It is characterized by gain of chromosomes, typically +X, +4, +6, +10, +14, +17, +18, and +21,+21; little is known about additional genetic aberrations. Approximately 20% of the patients relapse;...

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Huvudupphovsmän: Paulsson, Kajsa, Forestier, Erik, Lilljebjörn, Henrik, Heldrup, Jesper, Behrendtz, Mikael, Young, Bryan D., Johansson, Bertil
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2010
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3003126/
https://ncbi.nlm.nih.gov/pubmed/21098271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1006981107
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