Genetic landscape of high hyperdiploid childhood acute lymphoblastic leukemia

High hyperdiploid acute lymphoblastic leukemia (ALL) is one of the most common malignancies in children. It is characterized by gain of chromosomes, typically +X, +4, +6, +10, +14, +17, +18, and +21,+21; little is known about additional genetic aberrations. Approximately 20% of the patients relapse;...

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Main Authors: Paulsson, Kajsa, Forestier, Erik, Lilljebjörn, Henrik, Heldrup, Jesper, Behrendtz, Mikael, Young, Bryan D., Johansson, Bertil
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2010
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3003126/
https://ncbi.nlm.nih.gov/pubmed/21098271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1006981107
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