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Viral replicative capacity is the primary determinant of lymphocytic choriomeningitis virus persistence and immunosuppression

The Clone 13 (Cl13) strain of lymphocytic choriomeningitis virus is widely studied as a model of chronic systemic viral infection. Here, we used reverse genetic techniques to identify the molecular basis of Cl13 persistence and immunosuppression, the characteristics differentiating it from the close...

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Bibliografiske detaljer
Main Authors: Bergthaler, Andreas, Flatz, Lukas, Hegazy, Ahmed N., Johnson, Susan, Horvath, Edit, Löhning, Max, Pinschewer, Daniel D.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3003068/
https://ncbi.nlm.nih.gov/pubmed/21098292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1011998107
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