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Directed epitope delivery across the Escherichia coli outer membrane through the porin OmpF

The porins OmpF and OmpC are trimeric β-barrel proteins with narrow channels running through each monomer that exclude molecules > 600 Da while mediating the passive diffusion of small nutrients and metabolites across the Gram-negative outer membrane (OM). Here, we elucidate the mechanism by whic...

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Main Authors: Housden, Nicholas G., Wojdyla, Justyna A., Korczynska, Justyna, Grishkovskaya, Irina, Kirkpatrick, Nadine, Brzozowski, A. Marek, Kleanthous, Colin
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3003033/
https://ncbi.nlm.nih.gov/pubmed/21098297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1010780107
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