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Specific erythroid-lineage defect in mice conditionally deficient for Mediator subunit Med1

The Mediator complex forms the bridge between transcriptional activators and the RNA polymerase II. Med1 (also known as PBP or TRAP220) is a key component of Mediator that interacts with nuclear hormone receptors and GATA transcription factors. Here, we show dynamic recruitment of GATA-1, TFIIB, Med...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Stumpf, Melanie, Yue, Xiaojing, Schmitz, Sandra, Luche, Hervé, Reddy, Janardan K., Borggrefe, Tilman
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3003004/
https://ncbi.nlm.nih.gov/pubmed/21098667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1005794107
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