Natural Variation of the Amino-Terminal Glutamine-Rich Domain in Drosophila Argonaute2 Is Not Associated with Developmental Defects

The Drosophila argonaute2 (ago2) gene plays a major role in siRNA mediated RNA silencing pathways. Unlike mammalian Argonaute proteins, the Drosophila protein has an unusual amino-terminal domain made up largely of multiple copies of glutamine-rich repeats (GRRs). We report here that the ago2 locus...

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Hlavní autoři: Hain, Daniel, Bettencourt, Brian R., Okamura, Katsutomo, Csorba, Tibor, Meyer, Wibke, Jin, Zhigang, Biggerstaff, Jason, Siomi, Haruhiko, Hutvagner, Gyorgy, Lai, Eric C., Welte, Michael, Müller, H.-Arno J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2010
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3002974/
https://ncbi.nlm.nih.gov/pubmed/21253006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015264
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