A Universal Approach to Eliminate Antigenic Properties of Alpha-Gliadin Peptides in Celiac Disease

Celiac disease is caused by an uncontrolled immune response to gluten, a heterogeneous mixture of wheat storage proteins, including the α-gliadins. It has been shown that α-gliadins harbor several major epitopes involved in the disease pathogenesis. A major step towards elimination of gluten toxicit...

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Autores principales: Mitea, Cristina, Salentijn, Elma M. J., van Veelen, Peter, Goryunova, Svetlana V., van der Meer, Ingrid M., van den Broeck, Hetty C., Mujico, Jorge R., Monserrat, Veronica, Gilissen, Luud J. W. J., Drijfhout, Jan Wouter, Dekking, Liesbeth, Koning, Frits, Smulders, Marinus J. M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3002971/
https://ncbi.nlm.nih.gov/pubmed/21179575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015637
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