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A Universal Approach to Eliminate Antigenic Properties of Alpha-Gliadin Peptides in Celiac Disease

Celiac disease is caused by an uncontrolled immune response to gluten, a heterogeneous mixture of wheat storage proteins, including the α-gliadins. It has been shown that α-gliadins harbor several major epitopes involved in the disease pathogenesis. A major step towards elimination of gluten toxicit...

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Main Authors: Mitea, Cristina, Salentijn, Elma M. J., van Veelen, Peter, Goryunova, Svetlana V., van der Meer, Ingrid M., van den Broeck, Hetty C., Mujico, Jorge R., Monserrat, Veronica, Gilissen, Luud J. W. J., Drijfhout, Jan Wouter, Dekking, Liesbeth, Koning, Frits, Smulders, Marinus J. M.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3002971/
https://ncbi.nlm.nih.gov/pubmed/21179575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015637
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