Uptake of Aggregating Transthyretin by Fat Body in a Drosophila Model for TTR-Associated Amyloidosis

BACKGROUND: A functional link has been established between the severe neurodegenerative disorder Familial amyloidotic polyneuropathy and the enhanced propensity of the plasma protein transthyretin (TTR) to form aggregates in patients with single point mutations in the TTR gene. Previous work has led...

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Detaylı Bibliyografya
Asıl Yazarlar: Pokrzywa, Malgorzata, Dacklin, Ingrid, Vestling, Monika, Hultmark, Dan, Lundgren, Erik, Cantera, Rafael
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2010
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3002944/
https://ncbi.nlm.nih.gov/pubmed/21179560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014343
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