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Uptake of Aggregating Transthyretin by Fat Body in a Drosophila Model for TTR-Associated Amyloidosis

BACKGROUND: A functional link has been established between the severe neurodegenerative disorder Familial amyloidotic polyneuropathy and the enhanced propensity of the plasma protein transthyretin (TTR) to form aggregates in patients with single point mutations in the TTR gene. Previous work has led...

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Autors principals: Pokrzywa, Malgorzata, Dacklin, Ingrid, Vestling, Monika, Hultmark, Dan, Lundgren, Erik, Cantera, Rafael
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3002944/
https://ncbi.nlm.nih.gov/pubmed/21179560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014343
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