Detection of Heteroplasmic Mitochondrial DNA in Single Mitochondria

BACKGROUND: Mitochondrial DNA (mtDNA) genome mutations can lead to energy and respiratory-related disorders like myoclonic epilepsy with ragged red fiber disease (MERRF), mitochondrial myopathy, encephalopathy, lactic acidosis and stroke (MELAS) syndrome, and Leber's hereditary optic neuropathy...

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Detalhes bibliográficos
Main Authors: Reiner, Joseph E., Kishore, Rani B., Levin, Barbara C., Albanetti, Thomas, Boire, Nicholas, Knipe, Ashley, Helmerson, Kristian, Deckman, Koren Holland
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3002942/
https://ncbi.nlm.nih.gov/pubmed/21179558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014359
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