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Glycogenolysis in astrocytes supports blood-borne glucose channeling not glycogen-derived lactate shuttling to neurons: evidence from mathematical modeling

In this article, we examined theoretically the role of human cerebral glycogen in buffering the metabolic requirement of a 360-second brain stimulation, expanding our previous modeling study of neurometabolic coupling. We found that glycogen synthesis and degradation affects the relative amount of g...

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Hlavní autoři: DiNuzzo, Mauro, Mangia, Silvia, Maraviglia, Bruno, Giove, Federico
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3002884/
https://ncbi.nlm.nih.gov/pubmed/20827264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2010.151
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