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Changes in glucose uptake rather than lactate shuttle take center stage in subserving neuroenergetics: evidence from mathematical modeling

In this paper, we combined several mathematical models of cerebral metabolism and nutrient transport to investigate the energetic significance of metabolite trafficking within the brain parenchyma during a 360-secs activation. Glycolytic and oxidative cellular metabolism were homogeneously modeled b...

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Библиографические подробности
Главные авторы: DiNuzzo, Mauro, Mangia, Silvia, Maraviglia, Bruno, Giove, Federico
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2010
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2949148/
https://ncbi.nlm.nih.gov/pubmed/19888285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2009.232
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