Factors affecting the apparent efficacy and safety of tissue plasminogen activator in thrombotic occlusion models of stroke: systematic review and meta-analysis

Thrombolysis with recombinant tissue plasminogen activator (rtPA) improves outcome in animal models of stroke and in clinical trial, but is associated with increased intracranial hemorrhage. Here, we explore the impact of biologic and experimental design factors on efficacy and bleeding. We conducte...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Sena, Emily S, Briscoe, Catherine L, Howells, David W, Donnan, Geoffrey A, Sandercock, Peter A G, Macleod, Malcolm R
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2010
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3002882/
https://ncbi.nlm.nih.gov/pubmed/20648038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2010.116
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker