Method Development and Validation of Montelukast in Human Plasma by HPLC Coupled with ESI-MS/MS: Application to a Bioequivalence Study

A simple, sensitive, and specific LC-ESI–MS/MS method for quantification of Montelukast (MO) in human plasma using Montelukast-d(6) (MOD6) as an internal standard (IS) is discussed here. Chromatographic separation was performed on YMC-pack pro C(18), 50 x 4.6 mm, S-3 μm column with an isocratic mobi...

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Autors principals: Challa, Balasekhara Reddy, Awen, Bahlul Z., Chandu, Babu Rao, Khagga, Mukkanti, Kotthapalli, Chandrasekhar Bannoth
Format: Artigo
Idioma:Inglês
Publicat: Österreichische Apotheker-Verlagsgesellschaft 2010
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Original Papers
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3002811/
https://ncbi.nlm.nih.gov/pubmed/21179354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3797/scipharm.1002-07
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