Preparation and In Vitro/In Vivo Characterization of Porous Sublingual Tablets Containing Ternary Kneaded Solid System of Vinpocetine with β-Cyclodextrin and Hydroxy Acid

The demand for sublingual tablets has been growing during the previous decades especially for drugs with extensive hepatic first-pass metabolism. Vinpocetine, a widely used neurotropic agent, has low oral bioavailability due to its poor aqueous solubility and marked first-pass metabolism. Accordingl...

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Bibliografiska uppgifter
Huvudupphovsmän: Aburahma, Mona H., El-Laithy, Hanan M., Hamza, Yassin El-Said
Materialtyp: Artigo
Språk:Inglês
Publicerad: Österreichische Apotheker-Verlagsgesellschaft 2010
Ämnen:
Original Papers
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3002799/
https://ncbi.nlm.nih.gov/pubmed/21179352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3797/scipharm.0912-04
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