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Aminoglycoside-induced mutation suppression (stop codon readthrough) as a therapeutic strategy for Duchenne muscular dystrophy

Duchenne muscular dystrophy (DMD) is the most common, lethal, X-linked genetic disease, affecting 1 in 3500 newborn males. It is caused by mutations in the DMD gene. Owing to the large size of the gene, the mutation rate in both germline and somatic cells is very high. Nearly 13–15% of DMD cases are...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Malik, Vinod, Rodino-Klapac, Louise R., Viollet, Laurence, Mendell, Jerry R.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: SAGE Publications 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3002642/
https://ncbi.nlm.nih.gov/pubmed/21179598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1756285610388693
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