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In vivo effects of antibodies from patients with anti-NMDA receptor encephalitis: further evidence of synaptic glutamatergic dysfunction

BACKGROUND: A severe encephalitis that associates with auto-antibodies to the NR1 subunit of the NMDA receptor (NMDA-R) was recently reported. Patients' antibodies cause a decrease of the density of NMDA-R and synaptic mediated currents, but the in vivo effects on the extracellular glutamate an...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Manto, Mario, Dalmau, Josep, Didelot, Adrien, Rogemond, Véronique, Honnorat, Jérôme
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3002330/
https://ncbi.nlm.nih.gov/pubmed/21110857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1172-5-31
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