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In vivo effects of antibodies from patients with anti-NMDA receptor encephalitis: further evidence of synaptic glutamatergic dysfunction

BACKGROUND: A severe encephalitis that associates with auto-antibodies to the NR1 subunit of the NMDA receptor (NMDA-R) was recently reported. Patients' antibodies cause a decrease of the density of NMDA-R and synaptic mediated currents, but the in vivo effects on the extracellular glutamate an...

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Detalhes bibliográficos
Main Authors: Manto, Mario, Dalmau, Josep, Didelot, Adrien, Rogemond, Véronique, Honnorat, Jérôme
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3002330/
https://ncbi.nlm.nih.gov/pubmed/21110857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1172-5-31
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