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Dietary methyl donors, methyl metabolizing enzymes, and epigenetic regulators: diet–gene interactions and promoter CpG island hypermethylation in colorectal cancer

Dietary methyl donors might influence DNA methylation during carcinogenesis of colorectal cancer (CRC). Among 609 CRC cases and 1,663 subcohort members of the Netherlands Cohort Study on diet and cancer (n = 120,852), we estimated CRC risk according to methyl donor intake across genotypes of folate...

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Detalhes bibliográficos
Main Authors: de Vogel, Stefan, Wouters, Kim A. D., Gottschalk, Ralph W. H., van Schooten, Frederik J., de Goeij, Anton F. P. M., de Bruïne, Adriaan P., Goldbohm, R. Alexandra, van den Brandt, Piet A., van Engeland, Manon, Weijenberg, Matty P.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3002163/
https://ncbi.nlm.nih.gov/pubmed/20960050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10552-010-9659-6
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