Mff is an essential factor for mitochondrial recruitment of Drp1 during mitochondrial fission in mammalian cells

The cytoplasmic dynamin-related guanosine triphosphatase Drp1 is recruited to mitochondria and mediates mitochondrial fission. Although the mitochondrial outer membrane (MOM) protein Fis1 is thought to be a Drp1 receptor, this has not been confirmed. To analyze the mechanism of Drp1 recruitment, we...

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Bibliographic Details
Main Authors: Otera, Hidenori, Wang, Chunxin, Cleland, Megan M., Setoguchi, Kiyoko, Yokota, Sadaki, Youle, Richard J., Mihara, Katsuyoshi
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2010
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3002033/
https://ncbi.nlm.nih.gov/pubmed/21149567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201007152
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