Nevirapine pharmacokinetics when initiated at 200 mg or 400 mg daily in HIV-1 and tuberculosis co-infected Ugandan adults on rifampicin

BACKGROUND: Rifampicin lowers nevirapine plasma concentrations by inducing cytochrome P450. However, few data are available on this interaction during the lead-in period of nevirapine treatment. METHODS: Eighteen HIV-1/tuberculosis co-infected adults receiving rifampicin daily as part of anti-tuberc...

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Autori principali: Lamorde, Mohammed, Byakika-Kibwika, Pauline, Okaba-Kayom, Violet, Ryan, Mairin, Coakley, Peter, Boffito, Marta, Namakula, Rhoda, Kalemeera, Francis, Colebunders, Robert, Back, David, Khoo, Saye, Merry, Concepta
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2011
Soggetti:
Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3001850/
https://ncbi.nlm.nih.gov/pubmed/21047828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkq411
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