Phenotypic and genotypic characterization of influenza virus mutants selected with the sialidase fusion protein DAS181

BACKGROUND: Influenza viruses (IFVs) frequently achieve resistance to antiviral drugs, necessitating the development of compounds with novel mechanisms of action. DAS181 (Fludase(®)), a sialidase fusion protein, may have a reduced potential for generating drug resistance due to its novel host-target...

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Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Triana-Baltzer, Gallen B., Sanders, Rebecca L., Hedlund, Maria, Jensen, Kellie A., Aschenbrenner, Laura M., Larson, Jeffrey L., Fang, Fang
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2011
Konular:
Original Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3001847/
https://ncbi.nlm.nih.gov/pubmed/21097900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkq387
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