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Repeat-induced gene silencing of L1 transgenes is correlated with differential promoter methylation

Recent transgenic studies on L1 retrotransposons have afforded exciting insights into L1 biology, and a unique opportunity to model their function and regulation in vivo. Thus far, the majority of the transgenic L1 mouse lines are constructed via pronuclear microinjection, a procedure that typically...

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Detalhes bibliográficos
Main Authors: Rosser, James M., An, Wenfeng
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3001326/
https://ncbi.nlm.nih.gov/pubmed/20167267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gene.2010.02.005
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