Hereditary Pulmonary Alveolar Proteinosis: Pathogenesis, Presentation, Diagnosis, and Therapy

Rationale: We identified a 6-year-old girl with pulmonary alveolar proteinosis (PAP), impaired granulocyte-macrophage colony–stimulating factor (GM-CSF) receptor function, and increased GM-CSF. Objectives: Increased serum GM-CSF may be useful to identify individuals with PAP caused by GM-CSF recepto...

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Autori principali: Suzuki, Takuji, Sakagami, Takuro, Young, Lisa R., Carey, Brenna C., Wood, Robert E., Luisetti, Maurizio, Wert, Susan E., Rubin, Bruce K., Kevill, Katharine, Chalk, Claudia, Whitsett, Jeffrey A., Stevens, Carrie, Nogee, Lawrence M., Campo, Ilaria, Trapnell, Bruce C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Thoracic Society 2010
Soggetti:
F. Pediatrics and Lung Development
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3001266/
https://ncbi.nlm.nih.gov/pubmed/20622029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201002-0271OC
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