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Carcinoembryonic antigen interacts with TGF-β receptor and inhibits TGF-β signaling in colorectal cancers

As a tumor marker for colorectal cancers, CEA enhances the metastatic potential of cancer cells. CEA functions as an intercellular adhesion molecule and is up-regulated in a wide variety of human cancers. However, the molecular mechanisms by which CEA mediate metastasis remain to be understood. TGF-...

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Autors principals: Li, Ying, Cao, Hong, Jiao, Zhongxian, Pakala, Suresh B., Sirigiri, Divijendra Natha Reddy, Li, Wenpin, Kumar, Rakesh, Mishra, Lopa
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3001246/
https://ncbi.nlm.nih.gov/pubmed/20889724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-1073
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