Activation of p21(CIP1/WAF1) in Mammary Epithelium Accelerates Mammary Tumorigenesis and Promotes Lung Metastasis

While p21 is well known to inhibit cyclin-CDK activity in the nucleus and it has also been demonstrated to have oncogenic properties in different types of human cancers. In vitro studies showed that the oncogenic function of p21is closely related to its cytoplasmic localization. However, it is uncle...

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Bibliografiske detaljer
Main Authors: Cheng, Xiaoyun, Xia, Weiya, Yang, Jer-Yen, Hsu, Jennifer L., Chou, Chao-Kai, Sun, Hui-Lung, Wyszomierski, Shannon L., Mills, Gordon B., Muller, William J., Yu, Dihua, Hung, Mien-Chie
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3001223/
https://ncbi.nlm.nih.gov/pubmed/21040707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2010.10.126
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