Ribonucleotide reductase is not limiting for mitochondrial DNA copy number in mice

Ribonucleotide reductase (RNR) is the rate-limiting enzyme in deoxyribonucleoside triphosphate (dNTP) biosynthesis, with important roles in nuclear genome maintenance. RNR is also essential for maintenance of mitochondrial DNA (mtDNA) in mammals. The mechanisms regulating mtDNA copy number in mammal...

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Detalhes bibliográficos
Main Authors: Ylikallio, Emil, Page, Jennifer L., Xu, Xia, Lampinen, Milla, Bepler, Gerold, Ide, Tomomi, Tyynismaa, Henna, Weiss, Robert S., Suomalainen, Anu
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Molecular Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3001089/
https://ncbi.nlm.nih.gov/pubmed/20724444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq735
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