The Dyslexia-associated KIAA0319 Protein Undergoes Proteolytic Processing with γ-Secretase-independent Intramembrane Cleavage

The KIAA0319 gene has been associated with reading disability in several studies. It encodes a plasma membrane protein with a large, highly glycosylated, extracellular domain. This protein is proposed to function in adhesion and attachment and thought to play an important role during neuronal migrat...

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Bibliografiske detaljer
Main Authors: Velayos-Baeza, Antonio, Levecque, Clotilde, Kobayashi, Kazuhiro, Holloway, Zoe G., Monaco, Anthony P.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2010
Fag:
Cell Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3000997/
https://ncbi.nlm.nih.gov/pubmed/20943657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.145961
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