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Noncognate Mycobacterium tuberculosis Toxin-Antitoxins Can Physically and Functionally Interact

The Mycobacterium tuberculosis genome harbors a striking number (>40) of toxin-antitoxin systems. Among them are at least seven MazF orthologs, designated MazF-mt1 through MazF-mt7, four of which have been demonstrated to function as mRNA interferases that selectively target mRNA for cleavage at...

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Detalhes bibliográficos
Main Authors: Zhu, Ling, Sharp, Jared D., Kobayashi, Hiroshi, Woychik, Nancy A., Inouye, Masayori
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3000954/
https://ncbi.nlm.nih.gov/pubmed/20876537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.163105
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