The MBL2 ‘LYQA Secretor’ Haplotype Is an Independent Predictor of Postoperative Myocardial Infarction in Whites Undergoing Coronary Artery Bypass Graft Surgery

BACKGROUND: Mannose-binding lectin (MBL) is an important component of innate immunity and activator of the lectin complement pathway. Within the MBL2 gene are seven 5′ “secretor” haplotypes that code for altered serum MBL levels and complement activation. However, recent evidence suggests that 3′ MB...

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Hlavní autoři: Collard, Charles D., Shernan, Stanton K., Fox, Amanda A., Bernig, Toralf, Chanock, Stephen J., Vaughn, William K., Takahashi, Kazue, Ezekowitz, Alan B., Jarolim, Petr, Body, Simon C.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3000829/
https://ncbi.nlm.nih.gov/pubmed/17846289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.106.679530
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