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Efficient Utilization of Rare Variants for Detection of Disease-Related Genomic Regions

When testing association between rare variants and diseases, an efficient analytical approach involves considering a set of variants in a genomic region as the unit of analysis. One factor complicating this approach is that the vast majority of rare variants in practical applications are believed to...

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Detalhes bibliográficos
Main Authors: Zhang, Lei, Pei, Yu-Fang, Li, Jian, Papasian, Christopher J., Deng, Hong-Wen
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3000820/
https://ncbi.nlm.nih.gov/pubmed/21170328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014288
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