Common CD36 SNPs reduce protein expression and may contribute to a protective atherogenic profile

Membrane CD36 functions in the uptake of fatty acids (FAs), oxidized lipoproteins and in signal transduction after binding these ligands. In rodents, CD36 is implicated in abnormal lipid metabolism, inflammation and atherosclerosis. In humans, CD36 variants have been identified to influence free FA...

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Bibliografiske detaljer
Main Authors: Love-Gregory, Latisha, Sherva, Richard, Schappe, Timothy, Qi, Jian-Shen, McCrea, Jennifer, Klein, Samuel, Connelly, Margery A., Abumrad, Nada A.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2011
Fag:
Association Studies Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3000679/
https://ncbi.nlm.nih.gov/pubmed/20935172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddq449
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