Common CD36 SNPs reduce protein expression and may contribute to a protective atherogenic profile

Membrane CD36 functions in the uptake of fatty acids (FAs), oxidized lipoproteins and in signal transduction after binding these ligands. In rodents, CD36 is implicated in abnormal lipid metabolism, inflammation and atherosclerosis. In humans, CD36 variants have been identified to influence free FA...

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Hlavní autoři: Love-Gregory, Latisha, Sherva, Richard, Schappe, Timothy, Qi, Jian-Shen, McCrea, Jennifer, Klein, Samuel, Connelly, Margery A., Abumrad, Nada A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2011
Témata:
Association Studies Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3000679/
https://ncbi.nlm.nih.gov/pubmed/20935172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddq449
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