Developmental change in the electrophysiological and pharmacological properties of acid-sensing ion channels in CNS neurons

Acid-sensing ion channels (ASICs) are proton-gated cation channels that play important roles in the CNS including synaptic plasticity and acidosis-mediated neuronal injury. ASIC1a and ASIC2a subunits are predominant in CNS neurons, where homomultimeric and heteromultimeric channel configurations co-...

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Autores principales: Li, Minghua, Kratzer, Eric, Inoue, Koichi, Simon, Roger P, Xiong, Zhi-Gang
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Science Inc 2010
Materias:
Neuroscience
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3000580/
https://ncbi.nlm.nih.gov/pubmed/20724366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2010.192922
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