A Randomized Add-on Trial of an N-methyl-d-aspartate Antagonist in Treatment-Resistant Bipolar Depression

CONTEXT: Existing therapies for bipolar depression have a considerable lag of onset of action. Pharmacological strategies that produce rapid antidepressant effects—for instance, within a few hours or days—would have an enormous impact on patient care and public health. OBJECTIVE: To determine whethe...

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Autors principals: Diazgranados, Nancy, Ibrahim, Lobna, Brutsche, Nancy E., Newberg, Andrew, Kronstein, Phillip, Khalife, Sami, Kammerer, William A., Quezado, Zenaide, Luckenbaugh, David A., Salvadore, Giacomo, Machado-Vieira, Rodrigo, Manji, Husseini K., Zarate, Carlos A.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3000408/
https://ncbi.nlm.nih.gov/pubmed/20679587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/archgenpsychiatry.2010.90
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