Common MicroRNA Signatures in Cardiac Hypertrophic and Atrophic Remodeling Induced by Changes in Hemodynamic Load

BACKGROUND: Mechanical overload leads to cardiac hypertrophy and mechanical unloading to cardiac atrophy. Both conditions produce similar transcriptional changes including a re-expression of fetal genes, despite obvious differences in phenotype. MicroRNAs (miRNAs) are discussed as superordinate regu...

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Main Authors: El-Armouche, Ali, Schwoerer, Alexander Peter, Neuber, Christiane, Emmons, Julius, Biermann, Daniel, Christalla, Thomas, Grundhoff, Adam, Eschenhagen, Thomas, Zimmermann, Wolfram Hubertus, Ehmke, Heimo
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2010
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3000324/
https://ncbi.nlm.nih.gov/pubmed/21151612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014263
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