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Tracing entire operation cycles of molecular motor hepatitis C virus helicase in structurally resolved dynamical simulations
Hepatitis C virus helicase is a molecular motor that splits duplex DNA while actively moving over it. An approximate coarse-grained dynamical description of this protein, including its interactions with DNA and ATP, is constructed. Using such a mechanical model, entire operation cycles of an importa...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3000295/ https://ncbi.nlm.nih.gov/pubmed/21081697 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1014631107 |
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