Exogenously administered secreted frizzled related protein 2 (Sfrp2) reduces fibrosis and improves cardiac function in a rat model of myocardial infarction

Secreted frizzled related protein 2 (Sfrp2) is known as an inhibitor for the Wnt signaling. In recent studies, Sfrp2 has been reported to inhibit the activity of Xenopus homolog of mammalian Tolloid-like 1 metalloproteinase. Bone morphogenic protein 1 (Bmp1)/Tolloid-like metalloproteinase plays a ke...

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Bibliographische Detailangaben
Hauptverfasser: He, Wei, Zhang, Lunan, Ni, Aiguo, Zhang, Zhiping, Mirotsou, Maria, Mao, Lan, Pratt, Richard E., Dzau, Victor J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2010
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3000293/
https://ncbi.nlm.nih.gov/pubmed/21078975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1004708107
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