Secreted frizzled related protein 2 protects cells from apoptosis by blocking the effect of canonical Wnt3a

We have demonstrated that mesenchymal stem cells overexpressing the survival gene Akt can confer paracrine protection to ischemic myocytes both in vivo and in vitro through the release of secreted frizzled related protein 2 (Sfrp2). However, the mechanisms mediating these effects of Sfrp2 have not b...

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Bibliographische Detailangaben
Hauptverfasser: Zhang, Zhongyan, Deb, Arjun, Zhang, Zhiping, Pachori, Alok, He, Wei, Guo, Jian, Pratt, Richard, Dzau, Victor J
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2710029/
https://ncbi.nlm.nih.gov/pubmed/19109969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2008.11.016
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