Secreted frizzled related protein 2 protects cells from apoptosis by blocking the effect of canonical Wnt3a

We have demonstrated that mesenchymal stem cells overexpressing the survival gene Akt can confer paracrine protection to ischemic myocytes both in vivo and in vitro through the release of secreted frizzled related protein 2 (Sfrp2). However, the mechanisms mediating these effects of Sfrp2 have not b...

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Bibliografiske detaljer
Main Authors: Zhang, Zhongyan, Deb, Arjun, Zhang, Zhiping, Pachori, Alok, He, Wei, Guo, Jian, Pratt, Richard, Dzau, Victor J
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2710029/
https://ncbi.nlm.nih.gov/pubmed/19109969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2008.11.016
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