Transcription factor E4F1 is essential for epidermal stem cell maintenance and skin homeostasis

A growing body of evidence suggests that the multifunctional protein E4F1 is involved in signaling pathways that play essential roles during normal development and tumorigenesis. We generated E4F1 conditional knockout mice to address E4F1 functions in vivo in newborn and adult skin. E4F1 inactivatio...

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Hlavní autoři: Lacroix, Matthieu, Caramel, Julie, Goguet-Rubio, Perrine, Linares, Laetitia K., Estrach, Soline, Hatchi, Elodie, Rodier, Geneviève, Lledo, Gwendaline, de Bettignies, Carine, Thépot, Amélie, Deraison, Céline, Chébli, Karim, Hovnanian, Alain, Hainaut, Pierre, Dubus, Pierre, Sardet, Claude, Le Cam, Laurent
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2010
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3000279/
https://ncbi.nlm.nih.gov/pubmed/21088222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1010167107
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