Centrosomal protein of 192 kDa (Cep192) promotes centrosome-driven spindle assembly by engaging in organelle-specific Aurora A activation

Centrosomes are primary microtubule (MT)-organizing centers (MTOCs). During mitosis, they dramatically increase their size and MT-nucleating activity and participate in spindle assembly from spindle poles. These events require the serine/threonine kinase, Aurora A (AurA), and the centrosomal protein...

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Bibliographic Details
Main Authors: Joukov, Vladimir, De Nicolo, Arcangela, Rodriguez, Alison, Walter, Johannes C., Livingston, David M.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2010
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3000277/
https://ncbi.nlm.nih.gov/pubmed/21097701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1014664107
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